![]() ![]() Increase your damage, move speed, jump height, and health to become a walking tank, speed demon, pure damage or any other combination.įinely balance your spending across different chests, upgrading your skills is as important as trying a new gun or buying a new ability, make sure to prioritise correctly, as being too weak in an area could cause your death. ![]() Purchase and use several unique abilities to assist your fight, each catering to a different play style, whether or not ability is useful, is up to you, chain abilities together using secondary to further cater your gameplay. Use a range of satisfyingly visceral guns to eliminate zombies that drop like a sack of potatoes to your bullets, from SMG's to LMG's, ARS, and more, you're sure to find a gun that will suit your play style.įight several enemy types, all requiring a different strategy to take on, flying, shooting, sprinting and even exploding, you'll need to keep your wits about you. This is a roguelike, so be prepared for the usual, procedurally generated levels, stacks of enemies, and perma-death, no surprises here, except for the fact that to progress, you must take a leap of faith of the edge of the world. Sum() taking all the time and being the cause of the 'unwalkable' calls into nvlddmkm.sys, while true, is not the point.In fact, I had to edit my question to get a better (read: more obvious and trivial) MCVE, and thus this toy example. It was originally made by me, solo, in the 7-day BigFry game jam, in Unreal Engine 4, this version is the expanded and overhauled version, featuring more content. It features roguelike mechanics with several skills, guns and abilities to play with, including a variety of enemy types to shoot at. What you want to know is which lines of your program are responsible for the time, and those stats dont come near telling you.Heres how I do it. About This Game GROUND-UNBOUNDIs a procedurally generated high-intensity movement shooter with a retro wave art style.
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Like said, we could look back on this period as the period when we fought for our social rights, economic rights, our climate future, our democratic rights, and more. If Reddit and others don't face the same fate if they're ever threatened, and governments make sure things like redditsearch can operate withoutbeing threatened by companies, or those governments themselves, this could be the first time in history you can use date specific search to just look up past people's comments decades in the future.Īnyway, if the future is better than the present I think the most clearly discernable nostalgic view is the Political view, personal nicknames being the "Build Back Better Generation" view and The "Second Greatest Generation" view). Geocities, Orkut, MySpace all had their backlogs deleted. A lot of the time, whenever people talk about how free and great the internet was or how naive a-political, optimistic or whatever people were, I always find it really annoying how hard it seems to be to verify whether they're right or retconning unless it's about politics or public opinion, in which case they're usually obviously retconning. I also wonder how nostalgia is going to be affected by the fact that it will be far less difficult to just look up the past felt like to the people living it when it was the present. I'm personally not all that in-tone with what the people around me are up to, so my take is not really more informed than anyone else here's take IMO.īut first, 2 things for speculation: Given people are living longer and having less children, I wonder if there will ever be a point where having a relevant youth and youth culture will just become fundamentally less important, albeit maybe that's either already happened (well, the decreasing youth part, that is) or is happening too slowly for it to be definitive to any generation or group cohort. I was planning on doing this, but decided to do it later because I guessed I could make a list long enough for the comment section to gave less comment, which in hindsight is a pretty poorly-made guess, even if this is decently elaborate. The style is already shifting that asked me to give my opinion on the subject, mainly because this period's nostalgia will be my age group's nostalgia, being a younger teenager. The 2020s will be a mash-up of that angsty dark future style, and some colorful, baggy, eccentric 70s. A lot of leather, even though sadly not all that in style. Slim and sleek clothing, bright neon hairs, tattoos, and overall 'punk' style. Working against "The Man" and taking back control. The latter 2010s will be more akin to dark neon, cassette futurist in style, dystopian, worrisome, full of rebellion and anger. ![]() ![]() ![]() The movie "Perks of Being a Wallflower" will be considered the Definitive Film of that era, similar to Breakfast Club or 16 Candles are thought of as now. Similar to how we think of the early 80s before the neon. The movies will emphasize on bright, neutral, and pastel colors, idealistic thoughts and technology that is better suited for 2005-2009. Even though high waisted pants were only popular in the recent years, they will focus on them for this time frame. Hipsters were brought to the fore from 2010-2013. The early 2010s will be full of neutral colors, slimmer fitting clothing with a lot of sweatshirts and sweat pants, and a lot of beanies. ![]() Mr Marquardt is also widely recognised as the head bouncer for the Berlin techno club Berghain - often described as one of the most exclusive clubs in the world. “To view 5000 digital images during the shooting and to delete 4999 because they’re crap, that’s not my cup of tea,” he said. “The anticipation before seeing the results lasts for a few days - almost a luxury these days,” Mr Marquardt said. ![]() Mr Marquardt only uses film cameras, and the vast majority of his photos are black and white. Sven Marquardt is the famous bouncer of Berghain, the ‘nein’ man, celebrated photographer and now also a figure in the seventh art. “I’m inspired to show how I feel about my way of life, and I draw my inspiration from my surrounds and the people who I work with and the people who are near me, and that has stayed the same over the years.” “This exhibition is very much about Berlin,” Mr Marquardt said through a translator. Mr Marquardt began taking photos in the early 1980s in East Berlin. ![]() The 54-year-old Berlin photographer has just opened his first Australian exhibition Fotografien at The Substation in Newport. The clubs lead bouncer Sven Marquardt has made no secret of how difficult and non-specific the credentials are, stating that anyone from a suited-up lawyer to 'guys in masks' could be right, but. 1 feat.WITH his gold teeth, barbed wire face tattoos and heavy silver piercings, it’s impossible to mistake Sven Marquardt for anyone else. This is an absolute must-visit if you’re unsuccessful or uninterested in the drama of other Berlin clubs. This website simulates getting in (or not getting in) to Berghainįact Premiere: Aurélien Bernard - (reed) įact Premiere: Síbín Vol. the dress code is lax and the bouncers are generally welcoming. The site is the latest bit of savvy Berghain-related tech to have emerged in recent years, following last year’s app designed to tell you whether or not there’s currently a queueat the club, and a Flappy Bird-based video game that challenges you to navigate your way past infamous Berghain bouncer Sven Marquardt in a flurry of click-hops. The film starts with the fall of the Berlin Wall and features Baldwin, as well as two other prominent doormen, Sven Marquardt, the iconic Berghain bouncer with the heavily tattooed face, and Frank. If you’ve ever attempted to woo Berghain’s bouncers into letting you step through its hallowed doors only to be ushered away, head to the site now via Google Chrome to practice for your next attempt. It then takes you through a realistic simulation, which brings you outside the club and face-to-face with the doorman, who asks: “Have you been here before?”, “Are you drunk?” and “Do you know who’s spinning tonight?”. Share your result: made by sansho. Turn up the volume and say OKAY to start your training. From Berghains door to the silver screen: Sven Marquardt. The trainer needs access to your camera and microphone for analyzing your bodylanguage. Yes Sven Marquardt is an actor, photographer and bouncer I was so excited to see him in Chapter 4. Berghains notorious bouncer Sven Marquardt Credit: Getty Images Sven, somewhat surprisingly, is also a street photographer who, in the evenings, turns his artistic eye to curating Berghain’s. Berghains iconic bouncer Sven Marquardt joins cast of John Wick 4. Anyway, what an incredible film, don’t hesitate Youre right. He’s the facial tattoo guy, who repeats his name. They alone decide who is allowed to pass through. Get rejected by the club’s notoriously difficult-to-impress bouncers from the comfort of your own home.Ī new website simulates the experience of trying to get into infamous Berlin nightclub Berghain using face and voice recognition technology.īerghaintrainertakes a video of your face via your webcam and prompts you to talk into your computer’s microphone while it analyses your body language. Berghain bouncer (Sven) I thought one of the Berlin characters was the bouncer from Berghain, named Sven. As famous as the club itself is, so are the bouncers and their harsh regiment in Berghain. ![]() Receptor affinity and extracellular domain modifications affect tumor recognition by ROR1-specific chimeric antigen receptor T cells. Novel CD19/CD22 bicistronic chimeric antigen receptors outperform single or bivalent cars in eradicating CD19+CD22+, CD19- and CD22- Pre-B Leukemia. Long-term follow-up of CD19 CAR therapy in acute lymphoblastic leukemia. Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia. Intent to treat leukemia remission by CD19CAR T cells of defined formulation and dose in children and young adults. CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients. T cells expressing CD19 chimeric antigen receptors for acute lymphoblastic leukaemia in children and young adults: a phase 1 dose-escalation trial. One-year overall and event-free survival were 63% and 46%, respectively. Persistence was demonstrated in 11 of 14 patients at last follow-up, with enhanced CAR T cell expansion compared with published data. In a clinical study (CARPALL, NCT02443831), 12/14 patients with relapsed/refractory pediatric B cell acute lymphoblastic leukemia treated with CAT CAR T cells achieved molecular remission. CAT CAR T cells showed increased proliferation and cytotoxicity in vitro and had enhanced proliferative and in vivo antitumor activity compared with FMC63 CAR T cells. ![]() We generated a novel CD19 CAR (CAT) with a lower affinity than FMC63, the high-affinity binder used in many clinical studies 1, 2, 3, 4. There is evidence of a ceiling above which increased immunoreceptor affinity may adversely affect T cell responses 9, 10, 11. ![]() However, little is known about the impact of CAR binding affinity. Some factors, including the choice of single-chain spacer 6 and extracellular 7 and costimulatory domains 8, have a profound effect on CAR T cell function and persistence. Moreover, 40–60% of patients relapse owing to poor CAR T cell persistence or emergence of CD19 − clones. Nature Medicine volume 25, pages 1408–1414 ( 2019) Cite this articleĬhimeric antigen receptor (CAR)-modified T cells targeting CD19 demonstrate unparalleled responses in relapsed/refractory acute lymphoblastic leukemia (ALL) 1, 2, 3, 4, 5, but toxicity, including cytokine-release syndrome (CRS) and neurotoxicity, limits broader application. Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR ![]()
![]() ![]() The 109 ships consist of 70 liners that carry processed goods 22 tankers and 16 bulk carriers, both of which carry bulk commodities and 1 integrated tug/barge. Of these, 383 are active ships 109 of which participated in the food aid preference trade in cargo preference year 1987-88. oceangoing merchant marine fleet consisted of 661 active and inactive vessels. Tug Barge OperationsĪccording to MARAD, as of October 1, 1989, the U.S. Interlake invested $23 million in this vessel to meet increased demand for stone and other cargos on the Great Lakes. The integrated tug/barge PATHFINDER, owned by the Interlake Steamship Company of Cleveland, is longer than all but one of Cleveland's skyscrapers are tall. The PRESQUE ISLE was the second thousand foot vessel on the Great Lakes (the Erie-built STEWART CORT which came out in 1972 was the first). The 1,000-foot-long tug/barge PRESQUE ISLE has been serving the Great Lakes iron ore, coal and stone trades since 1973 and routinely carries more than 2.6 million tons of cargo each year. Here, barges are large units with carrying capacities that rival our largest self-propelled units. However, on the Great Lakes and the US coasts and non-contiguous trades, the word barge has a much different meaning. That image is correct for the inland rivers and they offset the smallish carrying capacity of individual barges by combining 15-20 units into one tow. ![]() The word barge evokes the image of a small, shallow draft unit with very limited carrying capacity that requires extensive shoreside equipment to be unloaded. No particular changes in the size or shape of the tug are required except for a higher pilot house, needed for improved visibility. Directional stability and control underway is far superior to that of a towed barge. In the most efficient systems, the tug is attached by trunion mountings protruding from the bow into sockets fitted along the inside of the barges recesses. The barge is built in the molded form of a normal ships hull. The stern is notched to accept a special tug which can be rigidly connected to the barge, forming a single vessel. Integrated tug/barge units are used widely in the US Gulf and east coast offshore trade. Integrated Tug Barge (ITB) / Tug/Barge Unit (TBU) We are welcoming all students who want to get the same experience that the celebrities had, but not only the celebrities but our current students have, to reach out to Alabama State University because we are a home waiting to expand the minds of our students,” said Dr. “.For the world to be able to see what goes on at Alabama State University is an exciting opportunity. Hornet Nation is encouraged to watch the show on television on BET+. ASU is entrenched in history, including being a part of the Civil Rights Movement,” O’Ryan pointed out. “‘I Swarm As 1.’ I learned that the ASU logo means to stick together and you can get it done faster and its more fun that way…I believe it’s very important to be around like-minded people and people who look like you that you can relate to when you are advancing in your life…I appreciate the ASU faculty, staff, and student body. O’Ryan said he would definitely recommend attending an HBCU, especially ASU. So, if you are looking to go to school or looking to come back to school, ASU is the place to be,” said Kwaylon. I went to a black school, Texas Southern, a shout out to them, but this school (ASU) just carries a different culture, a different energy. I had to really get into my studies…I can say this is 100 percent the school to go to. ![]() I think being an influencer / creator is kind of easy because we get slides versus ASU who didn’t care about the celebrity aspect we were treated like any other students. "My experience here got me back to being motivated to work hard. The celebrities also participated in a Q&A and an ASU Trivia Contest, hosted by Miss ASU 2022-23 Aleah Robinson and 2022-23 SGA Vice President Trent Martinez.īoth celebrities agreed that their experience at ASU was like none other. ![]() They joined the crowd in watching the screening, which was met with shouts of laughter and enthusiastic applause. At that moment, the sounds of the ASU Mighty Marching Hornets filled the air as the band escorted College Hill celebrities O’Ryan and Kwaylon into a room full of excited students. Ross then informed the crowd of a special surprise. We hope our participation will enhance the interest in not only Alabama State University but also all HBCUs.” “This is a unique opportunity to introduce ASU to new audiences. “ASU is excited for the opportunity for the world to see the academic excellence and the many talents that are here on the campus of ASU,” said Ross, who also thanked everyone involved, including the BET Plus Unscripted Team. The entire season will begin May 11 on BET+. welcomed students to the premiere screening of the first episode of Season 2. ![]() To celebrate BET shooting the reality show’s second season on the ASU campus, the University co-sponsored A “College Hill: Celebrity Edition” screening and Yard Fest on Tuesday, April 25, at the John Garrick Hardy Student Center.ĪSU President, Dr. The shooting lasted for four weeks, as camera crews swarmed the campus and major ASU events like The Magic City Classic, capturing the reality of the stars’ experience. Like any other college student, the celebrity students were required to attend classes, follow University policies, complete their coursework and take mid-terms and finals. Other cast members were reality star Tiffany “New York” Pollard, actress Parker McKenna Posey and returning star from season 1, singer/actor Ray J. Well, a select group of Alabama State University students had that chance during the Fall 2022 semester when the cast of BET’s “College Hill: Celebrity Edition Season 2” was enrolled at the University to work toward completing a specialty certificate program. Ross, Jr.Įver dreamed of sitting in class next to celebrities like model Amber Rose or studying at the library with basketball legend Iman Shumpert, R&B singer O’Ryan Browner or reality TV personality Joseline Hernandez! How about shooting a student film with social media star Kwaylon Rogers? BET’s “College Hill: Celebrity Edition Season 2” stars O'Ryan Browner, left, and Kwaylon Rogers, right, pose with Alabama State University President Quinton T. ![]() However, all subsequent frequency calculations using optimized geometries crash. Works fine with the Linux 64 Bit G09 (Revision A.02) version. Geometry optimization for neutral and sodiated species using e.g. ![]() I try to calculate sodium cation affinities with MP2=Full. I don’t clearly know how are the anlysi are done and what are the differences. I compared the outputs there is two series of normal analysis. Now, I understood that I need normal mode analysis using HPmodes syntax to feed the code. Then, I shifted to source code, FCClasses to follow up. However, the code is error prone! I got alot of error message without any documentation. I want to compute the vibronic spectra of some dyes. I would be grateful if you could explain me the difference between the normal analysis done using HPmodes and without that. One other thing, try to summarize your questions in a coherent way and please do not post entire output files! I don’t have the time to check them in their entirety. Feel free to reply to any comment you think you might have an answer to because the thing is, I don’t have all the answers (I wish I did, trust me). Please use tags at the begining of your comment, e.g.: #convergencefailure #visualization #gaussianerror or whatever you might think could help me, and others, to quickly find an answer to your queries. Therefore I open this new page for all those questions you have! I don’t intend to have a repository like the one on the CCL, of course, but at least we could organize the info and make it readily available for those who might need it in the end, that is what we do as scientists, right? Sometimes I get interesting questions that don’t quite fit into any of the existing topics already discussed within the blog and my obsessive/compulsive nature tells me that getting this questions in a random part/page/post of the blog doesn’t look quite neat either. ![]() However, the UW recommends that CADR courses be completed with a letter or numerical grade. A grade of “pass” in a “pass/not pass” will also count. In general, you must attain, at minimum, a passing grade (including D) to satisfy a CADR. ![]() Community college: 5-credit course SPAN 102 (counts as 1 CADR credit and attainment of second-year level).Community college: 5-credit English composition or literature course (counts as 1 CADR credit). ![]() Senior year math-based quantitative courseĮxamples of combining high school & college coursework English Science, including 2 years of lab science Alternative scheduling systems, such as block schedules, may also be counted as one credit for comparable course content. Usually, one CADR credit represents content covered in a full year course. In general, at the college level, five credits on a quarter system (or three credits on a semester system) equals one high school credit. However, students who completed a portion of the CADRs in high school may supplement high school courses with qualifying college courses, as long as they are completed before enrolling at the UW.ĬADRs completed in high school are expressed as high school credits. Transfer guidelines for special admission by appealĬollege Academic Distribution Requirements (CADRs)Īdmission to the UW requires completion of coursework in the subjects listed below - whether in high school, college or a combination of the two - unless you have earned 40 transferrable college quarter credits or more at the time of application (beginning with winter 2023 applicants).Īlmost all applicants will have satisfied CADRs through coursework completed in high school (generally defined as grades 9-12 in the U.S.).Lake Washington Institute of Technology.Alternatives to the English requirement for admission.College Academic Distribution Requirements (CADRs). ![]() So he got the Master’s, because he’d need that. This was a man with a plan, an elite football player at Ohio State whose NFL career was derailed by an enlarged heart, but a man whose charisma and intelligence were so large that his future in coaching was assured. More: Video naming Marcus Freeman as Notre Dame's coach has fans 'ready to run through a brick wall' Please, Marcus, be who everyone says you are. Right now all we have is a vague outline – who is Marcus Freeman? – but with his help, we’ll fill the gaps as we go. ![]() Does the reaction to the video introducing him as the new Irish coach – it's love at first sight – prove it? No.īut it’s a start. Does any of that prove he’s a wonderful human being? No. Marcus Freeman married his college sweetheart, then went back to school in 2011 to get his Master’s degree. I have a lot more to say about you.īut first, to cleanse my palate, to feel good again about college sports – to express my affection, finally, for Notre Dame football – let’s talk about Marcus Freeman, the man Notre Dame just hired to replace Brian Kelly. This guy is your problem now, LSU, but don’t stop reading just yet. “Any negative criticism about me now is because we're 4-7,” he said in 2016, demonstrating his philosophy on coaching a big-time football program:īad stuff is bad only if we don’t win enough. Didn’t humble him, either.Īfter the alleged rape of Seeberg in August 2010, after the death of Declan Sullivan two months later, Kelly was so humbled by it all that he decided the punishment in 2016 for academic fraud in his program, involving a student athletic trainer and three players, was overstated. Mary’s College student Lizzy Seeberg, with Seeberg committing suicide 10 days after the alleged assault – didn’t slow him down. He won so many games, other issues you’d think would derail a man’s coaching career – truly unthinkable issues like a student-manager falling to his death from a 50-foot hydraulic scissor lift after being sent up there on a frighteningly windy day like a linebacker being accused of raping St. ![]() More: 5 things to know about Notre Dame's new head coach Marcus Freeman The power of the pen isn’t nearly as mighty as the power of winning a lot of football games. Five years ago, when the long list of problems in Kelly’s program suddenly included the unthinkable – NCAA violations stemming from academic fraud … at Notre Dame – I said he should be fired. Hey, is it OK to admit I never liked Brian Kelly? Shouldn’t be that big a surprise. Brian Kelly is gone, and defensive coordinator Marcus Freeman is staying, and finally the Irish have a coach to rally behind. It’s OK to like Notre Dame football again. |